XTerra* Columns for the Best Peak Shape at all pH levels (1-12)

    The inability to adequately reduce the number of silanols on a silica surface by more than 50%, despite extensive bonding procedures, puts limits on the peak symmetry in your methods. This makes it more difficult for you to work with generic methods particularly for strongly basic compounds. Because hydrid particles are partially organic (they have methlysiloxane units in place of one third of the SiO2 units), they yield bonded phases with increased surface coverage reducing concentrations of residual silanols. As such, Xterra* columns deliver a significant reduction in peak tailing for basic compounds. Now you can develop more reliable generic methods by maximizing peak capacity, and increase the senesitivity of methods by providing the most symmetrical peak shape.

Long Lifetime

    Columns that last longer save you money. Symmetry* columns can last for over 10,000 injections with:
    ● minimal loss in efficiency
    ● minimal increase in backpressure
    ● minimal change in retention time
    Symmetry* columns deliver guaranteed consistent performance because Waters optimized the two key factors that control column lifetime:
    ● hydrolytic stability of the packing material
    ● mechanical stability of the packed bed

HPLC Columns and Cartridges for Protein and Peptide Pharmaceutical Analysis

    ● High recoveries of peptides and proteins
    ● Unmatched column-to-column reproducibility
    ● Extended column lifetimes
    ● Sharpest peaks for highest resolution

Waters Spherisorb* Products

    Waters Spherisorb* columns are the most widely referenced HPLC columns in the scientific literature. There are over 2000 analytical abstract published on Waters Spherisorb* columns, providing a fremendous range of validated methods and applications to assist you in your method development process.
    One of the great advantages of choosing Waters Spherisorb* columns is the range of choices available to you. Waters Spherisorb* Column are produced in a wide range of sizes and bonded phases to meet your chromatographic needs. Silica is produced in 3, 5 and 10 micron particle sizes. The high quality bonded phases give many different and unique separation selectivities.